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Coagulation

Data on coagulation detailed by researchers at University of North Carolina

Published in Proteomics Weekly, May 5th, 2008

According to a study from the United States, "D-dimer is a hemostasis marker that reflects ongoing fibrin formation and degradation. There is significant inter-individual and inter-population variability in D-dimer concentration, but whether genetic factors underlie these differences is largely unknown."

"We hypothesized that common coagulation gene variants contribute to differences in circulating D-dimer concentration. The setting was European-American (EA; n = 1858) and African-American (AA; n = 327) unrelated older adults from the Cardiovascular Health Study (CHS), in which we genotyped SNPs in 42 genes related to blood coagulation and fibrinolysis. Several...

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