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Angiogenesis

Researchers from Shanghai Jiao Tong University, Medical Department publish new studies and findings in the area of angiogenesis

Published in Proteomics Weekly, May 5th, 2008

According to recent research published in the journal Oncogene, "Angiogenesis and hematopoiesis are closely linked and interactive with each other, but few studies were given to identify possible links between angiogenesis-promoting proteins and hematopoiesis-related transcription factors. Here we investigated the potential relationship of oxygen-sensitive alpha-subunit of angiogenesis-related hypoxia-inducible factor-1 alpha (HIF-1 alpha) with Runt-related protein 1 (Runx1, also known as acute myeloid leukemia-1, AML-1), an important hematopoietic transcription factor."

"The results demonstrated that Runx1 and HIF-1 alpha proteins directly interacted with each...

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