Behavior
Study results from H. Busch and colleagues update understanding of behavior
Published in Proteomics Weekly, October 27th, 2008
According to recent research from Heidelberg, Germany, "Translation of large-scale data into a coherent model that allows one to simulate, predict and control cellular behavior is far from being resolved. Assuming that long-term cellular behavior is reflected in the gene expression kinetics, we infer a dynamic gene regulatory network from time-series measurements of DNA microarray data of hepatocyte growth factor-induced migration of primary human keratinocytes."
"Transferring the obtained interactions to the level of signaling pathways, we predict in silico and verify in vitro the necessary and sufficient time-ordered events that control migration. We show that...
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Source: Proteomics Weekly (2008-10-27)
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