Life Sciences
Study findings from German Cancer Research Center provide new insights into life sciences
Published in Proteomics Weekly, January 26th, 2009
New research, 'Tetrafluorophenolate of HBED-CC: a versatile conjugation agent for 68Ga-labeled small recombinant antibodies,' is the subject of a report. "The success of (68)Ga-labeled peptides for positron emission tomography of neuroendocrine tumors is mainly depending on the complex chemistry of this radioisotope. 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA), the chelator of choice has however limitations if its application is expanded to heat-sensitive proteins. Recombinant antibodies like single chain Fv or diabodies belong to this class of proteins," scientists writing in the European Journal of Nuclear Medicine and Molecular Imaging report.
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Source: Proteomics Weekly (2009-01-26)
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