DNA Research

Research from M. Wang and co-researchers in the area of DNA research described

Published in Proteomics Weekly, April 20th, 2009

According to recent research published in the journal Analytical Chemistry, "In many settings, molecular testing is needed but unavailable due to complexity and cost. Simple, rapid, and specific DNA detection technologies would provide important alternatives to existing detection methods."

"Here we report a novel, rapid nucleic acid detection method based on the accelerated photobleaching of the light-sensitive cyanine dye, 3,3'-diethylthiacarbocyanine iodide (DiSC(2)(3) I-), in the presence of a target genomic DNA and a complementary peptide nucleic acid (PNA) probe. On the basis of the UV-vis, circular dichroism, and fluorescence spectra of DiSC(2)(3) with...

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Source: Proteomics Weekly (2009-04-20)

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