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Proteomics Weekly

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Hepatitis E Virus



Research on hepatitis E virus described by H.X. Ma and colleagues



June 15th, 2009

According to recent research from Beijing, People's Republic of China, "Following infection with hepatitis E virus (HEV), anti-HEV immunoglobulin (Ig) M is thought to develop before anti-HEV IgG and to be a better marker for differentiating between the acute and convalescent phases of infection. In order to select polypeptides for improved detection of anti-HEV IgM, six and three overlapping polypeptides from open reading frames (ORFs) 2 and 3, respectively, of HEV genotypes 1 and 4 were expressed as fusion proteins in Escherichia coli."

"The reactivities of the polypeptides with anti-HEV IgM were evaluated using immunoblotting and enzyme immunoassays (EIAs). The data...


Source: Proteomics Weekly (2009-06-15)

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