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Acute Pancreatitis
Studies from J. Ockenga and colleagues reveal new findings on acute pancreatitis
June 15th, 2009
According to a study from Bremen, Germany, "Chronic pancreatitis (CP) and pancreatic adenocarcinoma (pCA) are associated with risk factors such as alcohol intake and tobacco smoking. Microsomal epoxide hydrolase (EPHX1) is a phase II detoxifying enzyme capable of tobacco-borne toxicant inactivation." "We studied the role of the EPHX1 c.337T >C (p.Y113H) variant, which leads to altered enzyme activity, in pancreatic diseases. We genotyped 2391 patients by melting curve analysis. We enrolled 367 patients with pCA, 341 patients with alcoholic CP (aCP), 431 patients with idiopathic CP or hereditary pancreatitis, 192 patients with acute pancreatitis, and 679 controls of...
Source: Proteomics Weekly (2009-06-15)
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