Published in Proteomics Weekly, June 29th, 2009
"Here, we studied cytokine-induced apoptosis in the pancreatic beta cell line INS-1 and performed a comparative mitochondrial protein pattern analysis using two-dimensional difference gel electrophoresis (2D-DIGE). Cytokine incubation of INS-1 cells increased caspase-3 activity about 3-fold, Which was reduced by 60% in the presence of exendin-4. Production of reactive...
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