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Proteomics Weekly

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Newcastle Disease



Data on Newcastle disease reported by D. Liu and co-researchers



July 13th, 2009

"C3d, a split product of C3, interacts with its receptor (CR2 or CD21) on B cells and follicular dendritic cells (FDCs) and is crucial for induction and maintenance of a normal humoral immune response. The gene fragment coding for Ross chicken C3d gene (chC3d) was cloned and expressed as a component of fusion proteins destined for its application in the vaccine study of chicken, and for in vitro experiments," scientists in Shandong, People's Republic of China report.

"Three potential vaccine construct units were engineered to contain two, four, and six copies of chC3d-P29 coding gene, which was linked to the F gene of Newcastle disease virus (NDV), an economically...


Source: Proteomics Weekly (2009-07-13)

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