Fusion Proteins
New findings from McMaster University describe advances in fusion proteins
Published in Proteomics Weekly, August 10th, 2009
According to a study from Hamilton, Canada, "In this paper, we report the formation of protein based liquid droplets resulting in the formation of in vivo microcompartments in E coli or tobacco cells. These microcompartments were generated by expressing elastin-like polypeptides (ELP), which have the ability to undergo a reversible phase transition, resulting in the formation of an aqueous two-phase system (ATPS) in the cytoplasm of the cell."
"We prove that these microcompartments are liquid by expressing a fusion protein consisting of ELP and GFP and by performing fluorescence recovery after photobleaching (FRAP) experiments at different stages of cell cultivation. In...
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Source: Proteomics Weekly (2009-08-10)
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