Research

Mice can eat 'junk' and not get fat

Published in Proteomics Weekly, September 21st, 2009

A study in the September 4th issue of the journal Cell, a Cell Press publication, identifies a gene that springs into action in response to a high fat diet. Mice that lack the gene become essentially immune to growing obese, regardless of their eating habits.

The protein encoded by the gene known as I'B kinase e (IKKe) belongs to a class of enzymes, the kinases, which typically make for good drug targets because they are relatively easy to block, according to the researchers. Even better in terms of its therapeutic promise, IKKe loss seems to have many beneficial effects. Mice without the gene are protected against weight gain, chronic inflammation, fatty liver and...

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Source: Proteomics Weekly (2009-09-21)

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