Epizyme, Inc.
NATURE REVIEWS DRUG DISCOVERY Publishes Epizyme-authored Paper on Protein Methyltransferases
Published in Proteomics Weekly, September 21st, 2009
A paper underscoring the importance of protein methyltransferases (PMTs) in drug discovery is published in the September 2009 online issue of NATURE REVIEWS DRUG DISCOVERY. Scientists Dr. Robert A. Copeland and Dr. Victoria M. Richon from Epizyme, Inc. in their paper entitled "Protein methyltransferases as a target class for drug discovery" conclude that "The structures and enzymatic mechanisms of the PMTs support the view that pharmacological modulation of these enzymes by small-molecule inhibitors will be an effective means of therapeutic intervention in cancer and numerous other unmet medical needs." The paper describes the PMT enzymes and the convergent biological and structural data...
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Source: Proteomics Weekly (2009-09-21)
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