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Journal of the National Cancer Institute

News brief: Merkel cell polyomavirus associated with Merkel cell carcinoma

Published in Proteomics Weekly, October 5th, 2009

The Merkel cell polyomavirus (MCPyV) is the only human polyomavirus known to be associated with a rare skin cancer, known as Merkel cell carcinoma, according to a new study published online September 23 in the Journal of the National Cancer Institute.

The majority of patients with Merkel cell carcinoma carry MCPyV, but little is known about the polyomavirus' prevalence in the general population and the association between circulating antibodies against MCPyV and the rare skin cancer.

Denise A. Galloway, Ph.D. and Paul Nghiem, M.D., Ph.D., of Fred Hutchinson Cancer Research Center in Seattle, and colleagues investigated the levels of antibodies...

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