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Buck Institute for Age Research

'Anti-Atkins' low protein diet extends lifespan in flies

Published in Proteomics Weekly, October 19th, 2009

Flies fed an "anti-Atkins" low protein diet live longer because their mitochondria function better. The research, done at the Buck Institute for Age Research, shows that the molecular mechanisms responsible for the lifespan extension in the flies have important implications for human aging and diseases such as obesity, diabetes and cancer.

The findings, which appear in the October 2 edition of Cell, also provide a new level of understanding of the regulation of mitochondrial genes and open new avenues of inquiry into the interplay between mitochondrial function, diet and energy metabolism.

Mitochondria act as the "powerhouse" of the cells. It is well...

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