According to recent research from Shanghai, People's Republic of China, "In screening 87665 unrelated healthy blood donors in China, serology studies resulted in the detection of two K-0 probands, both female. To explore the molecular basis of the K-null phenotype in the Chinese population, genomicDNA, total RNA, and reticulocyte RNA were subsequently prepared from the two probands, five family members of proband 1, four unrelated normal controls, and one unrelated KEL1 control."
"Nucleic acids were analyzed for the KEL gene by DNA and RNA sequencing, while antigens were analyzed by flow cytometry with BRIC18, BRIC68, anti-k, and anti-Kp(b). Two novel K-null alleles...
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