Eosinophilia
Researchers at Emory University publish new data on eosinophilia
Published in Proteomics Weekly, November 30th, 2009
According to recent research published in the American Journal of Clinical Pathology, "Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is an ulcerative lesion of the oral mucosa with unknown pathogenesis. A few recent case reports have demonstrated molecular evidence of T-cell clonality in TUGSE and CD30 immunoreactivity in the large atypical mononuclear cells, raising the possibility that a TUGSE subset may represent the oral counterpart of primary cutaneous CD30+ T-cell lymphoproliferative disorders."
"We examined the immunoreactivity for CD30 and T-cell receptor (TCR) 7 gene rearrangement in 3 7 TUGSE cases. Clonal TCR gene rearrangements were...
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Source: Proteomics Weekly (2009-11-30)
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