Hepatitis C Virus
Reports outline hepatitis C virus study findings from K.L. Pan and colleagues
Published in Proteomics Weekly, December 7th, 2009
"A cell culture system for the production of hepatitis C virus (HCV) whole virions has greatly accelerated studies of the virus life cycle and the discovery of anti-HCV agents. However, the quantification of the HCV titers in a whole-virus infection/replication system currently relies mostly on reverse transcription-PCR or immunofluorescence assay, which would be cumbersome for high-throughput drug screening," scientists in Taiwan report.
"To overcome this problem, this study has generated a novel cell line, Huh7.5-EG(Delta 4B5A) SEAP, that carries a dual reporter, EG(Delta 4B5A) SEAP. The EG(Delta 4B5A) SEAP reporter is a viral protease-cleavable fusion protein in...
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Source: Proteomics Weekly (2009-12-07)
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