Fusion Proteins
Researchers from Louisiana State University discuss findings in fusion proteins
Published in Proteomics Weekly, February 1st, 2010
According to recent research published in the journal Biochemistry, "The myogenic transcription factor Pax3 plays an essential role in early skeletal muscle development and is a key component in alveolar rhabdomyosarcoma (ARMS), a childhood solid muscle tumor. ARMS is characterized by a t(2;13) chromosomal translocation resulting in the fusion of the 5' Pax3 sequences to the 3' FOXO1 sequences to encode the oncogenic fusion protein, Pax3-FOXO1."
"Posttranslational modifications such as phosphorylation are common mechanisms by which transcription factors are regulated. Consistent with this fact, we demonstrated in a previous report that Pax3 is phosphorylated on...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Proteomics Weekly
Source: Proteomics Weekly (2010-02-01)
More Articles from Proteomics Weekly
- American College of Radiology / American Roentgen Ray Society
Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer - 4SC AG
4SC Announces Start of Dosing in First-in-Man Phase I Study with 4SC-203 - Enzyme Research
Reports summarize enzyme research research from L. Lartigue and co-authors - Fusion Proteins
Research from National Chiao Tung University in the area of fusion proteins published - Fusion Proteins
Research on fusion proteins described by J.L. Fast and colleagues - Life Sciences
Inje University publishes research in life sciences - More from this issue of Proteomics Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
