Proteomics

Study results from M.Q. Lu and colleagues broaden understanding of proteomics

Published in Proteomics Weekly, June 7th, 2010

According to a study from the United States, "Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) plays an essential role in the life cycle of the virus. Therefore. RT has been a primary target in the development of antiviral agents against HIV-1."

"Given the prevalence of resistant viruses, evaluation of the resistance profile of potential drug candidates is a key step in drug development. A simplified RI purification protocol would facilitate this process, as it provides an efficient method by which to purify RT variants for compound evaluation. Traditional purification protocols require the use of several columns to purify untagged RT. The entire...

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Source: Proteomics Weekly (2010-06-07)

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