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Lipid Research

Investigators at University of North Carolina, Lineberger Comprehensive Cancer Center target lipid research

Published in Proteomics Weekly, June 7th, 2010

Researchers detail in 'Phosphoinositide phosphatases in cell biology and disease,' new data in lipid research. "Phosphoinositides are essential signaling molecules linked to a diverse array of cellular processes in eukaryotic cells. The metabolic interconversions of these phospholipids are subject to exquisite spatial and temporal regulation executed by arrays of phosphatidylinositol (PtdIns) and phosphoinositide-metabolizing enzymes," researchers in the United States report.

"These include PtdIns-and phosphoinositide-kinases that drive phosphoinositide synthesis, and phospholipases and phosphatases that regulate phosphoinositide degradation. In the past decade,...

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