Structural Biology
New structural biology study findings have been reported by scientists at Merck & Company, Inc.
Published in Proteomics Weekly, July 19th, 2010
Current study results from the report, 'Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase,' have been published. According to recent research from the United States, "The unique S28 family of proteases is comprised of the carboxypeptidase PRCP and the aminopeptidase DPP7. The structural basis of the different substrate specificities of the two enzymes is not understood nor has the structure of the S28 fold been described."
"The experimentally phased 2.8 A crystal structure is presented for human PRCP. PRCP contains an alpha/beta hydrolase domain harboring the catalytic Asp-His-Ser triad and...
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Source: Proteomics Weekly (2010-07-19)
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