Dermatology
Reports outline dermatology study results from Pola Chemical Industries, Inc.
Published in Proteomics Weekly, August 16th, 2010
Scientists discuss in 'Perturbation of lamellar granule secretion by sodium caprate implicates epidermal tight junctions in lamellar granule function' new findings in dermatology. "Polarized secretion of lamellar granules (LGs) delivers various lipids, proteases, and protease inhibitors into the stratum corneum (SC) of the epithelium. Disruption of LGs is associated with severe cutaneous diseases, but the mechanism of their polarized secretion is not known," investigators in Yokohama, Japan report.
"On the other hand, recent study shows epidermal tight junctions (TJs) localize in stratum granulosum (SG), and TJs are involved in polarized molecule secretion. Thus, we...
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Source: Proteomics Weekly (2010-08-16)
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