Enzymes and Coenzymes

New enzymes and coenzymes study findings have been reported from D.M. Chung et al

Published in Proteomics Weekly, August 16th, 2010

"A novel Allium tuberosum fibrinolytic enzyme (ATFE) was purified from the leaf of chive by ion exchange chromatography followed by gel filtration. The molecular mass and iso-electric point (pI) of ATFE were 90 kDa and 4.0 by using 1- or 2-D fibrin zymography, respectively," scientists in South Korea report.

"ATFE was optimally active at pH 4.0 and 40 degrees C. ATFE had a high degrading activity for the A alpha-chain of human fibrinogen and hydrolyzed the B beta-chain slowly, but did not affect the gamma-chain, indicating that it is a alpha-fibrinogenase. The proteolytic activity of ATFE was inhibited completely by phenylmethylsulfonyl fluoride (PMSF), indicating that...

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Source: Proteomics Weekly (2010-08-16)

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