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DNA Research

Data on DNA research discussed by researchers at Vrije University

Published in Proteomics Weekly, October 18th, 2010

Researchers detail in 'Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging,' new data in dna research. According to recent research from Netherlands, "Single-molecule manipulation studies have revealed that double-stranded DNA undergoes a structural transition when subjected to tension. At forces that depend on the attachment geometry of the DNA (65 pN or 110 pN), it elongates approximately 1.7-fold and its elastic properties change dramatically."

"The nature of this overstretched DNA has been under debate. In one model, the DNA cooperatively unwinds, while base pairing remains intact. In a competing model, the...

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