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Dystrophin-Associated Proteins

Reports from University of Sheffield add new data to research in dystrophin-associated proteins

Published in Proteomics Weekly, October 18th, 2010

Fresh data on dystrophin-associated proteins are presented in the report 'Modulation of cell spreading and cell-substrate adhesion dynamics by dystroglycan.' According to recent research from Sheffield, the United Kingdom, "Dystroglycan is a ubiquitously expressed cell adhesion protein. Its principal role has been determined as a component of the dystrophin-glycoprotein complex of muscle, where it constitutes a key component of the costameric cell adhesion system."

"To investigate more fundamental aspects of dystroglycan function in cell adhesion, we examined the role of dystroglycan in the dynamics and assembly of cellular adhesions in myoblasts. We show that...

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