Research findings from South China University of Technology update understanding of protein science

2010 DEC 13 -- Fresh data on protein science are presented in the report 'New insights into S2P signaling cascades: regulation, variation, and conservation.' "Regulated intramembrane proteolysis (RIP) is a conserved mechanism that regulates signal transduction across the membrane by recruiting membrane-bound proteases to cleave membrane-spanning regulatory proteins. As the first identified protease that performs RIP, the metalloprotease site-2 protease (S2P) has received extensive study during the past decade, and an increasing number of S2P-like proteases have been identified and studied in different organisms; however, some of their substrates and the related S1Ps remain...

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