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New Medical Research Study Findings Reported from University of Uppsala

Published in Proteomics Weekly, October 17th, 2011

2011 OCT 17 -- Data detailed in "A screening method for phosphohistidine phosphatase 1 activity" have been presented. According to the authors of recent research from Uppsala, Sweden, "Abstract Introduction. Research in the field of protein-bound phosphohistidine phosphorylation has been hampered by the difficulties in analysis and detection of phosphohistidine."

"Therefore a screening method was developed primarily for the analysis of phosphohistidine phosphatase 1 (PHPT1) activity. A highly positively charged substrate, Ac-Val-Arg-Leu-Lys-His-Arg-Lys-Leu-Arg-pNA, containing the peptide surrounding the phosphorylated histidine in ion channel KCa3.1 was...

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