Transcription Factors

Research on Transcription Factors Detailed by Investigators at Wuhan University

Published in Proteomics Weekly, February 27th, 2012

2012 FEB 27 -- According to the authors of recent research from Wuhan, People's Republic of China, "CREB-binding protein (CBP) belongs to a unique class of transcription co-activators possessing histone acetyltransferase (HAT) activity. The aim of the present study was to evaluate the role of CBP in thrombin-induced endothelial activation, and also explore the underlying mechanism."

"Leukocyte-endothelial adhesion was calculated as the proportion of the labeled-neutrophils that adhered to ECs relative to all neutrophils applied. Levels of adhesion molecules were analyzed by real-time RT-PCR and western blot. Electrophoretic mobility shift assay and NF-kappa...

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Source: Proteomics Weekly (2012-02-27)

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