Proteomics

Data from Sanford Burnham Medical Research Institute Advance Knowledge in Proteomics

Published in Proteomics Weekly, March 5th, 2012

2012 MAR 5 -- "Phage display technology is an emerging drug discovery tool. Using that approach, short peptides that mimic part of a carbohydrate's conformation are selected by screening a peptide-displaying phage library with anti-carbohydrate antibodies," scientists writing in the journal Glycobiology report.

"Chemically synthesized peptides with an identified sequence have been used as an alternative ligand to carbohydrate-binding proteins. These peptides represent research tools useful to assay the activities of glycosyltransferases and/or sulfotransferases or to inhibit the carbohydrate-dependent binding of proteins in vitro and in vivo....

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Source: Proteomics Weekly (2012-03-05)

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