Proteomics
Reports from Kyoto University Advance Knowledge in Proteomics
Published in Proteomics Weekly, March 26th, 2012
2012 MAR 26 -- A report, "Stimulation of CK2-dependent Grp94 phosphorylation by the nuclear localization signal peptide," is newly published data in Molecular and Cellular Biochemistry. "The nuclear localization signal sequence (NLS) of SV40 Large T antigen is essential and sufficient for the nuclear translocation of the protein. Phosphorylation often modulates the intracellular distribution of signaling proteins," researchers in Kyoto, Japan report.
"In this study, we investigated effects of the NLS-peptide of Large T antigen on protein phosphorylation. When crude cell lysates were incubated with ['-(32)P]ATP, phosphorylation of several endogenous...
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Source: Proteomics Weekly (2012-03-26)
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