Studies from National Cancer Center Further Understanding of Nanorods

2012 MAR 26 -- Investigators discuss in "Photosensitizer-conjugated gold nanorods for enzyme-activatable fluorescence imaging and photodynamic therapy" new findings in Nanorods. "We report on the development of photosensitizer-conjugated gold nanorods (MMP2P-GNR) in which photosensitizers were conjugated onto the surface of gold nanorods (GNR) via a protease-cleavable peptide linker. We hypothesized that fluorescence and phototoxicity of the conjugated photosensitizers would be suppressed in their native state, becoming activated only after cleavage by the target protease matrix metalloprotease-2 (MMP2)," researchers in Gyeonggi Do, South Korea report.

...

Want to see the full article?

• Purchase this article for only $3.00