SARS
Recent findings in SARS provide new insights
Published in Respiratory Therapeutics Week, October 3rd, 2005
Study 1: The structure of the SARS coronavirus (SARS-CoV) frameshift signal has been elucidated, and a possible therapeutic target has been identified.
"A wide range of RNA viruses use programmed -1 ribosomal frameshifting for the production of viral fusion proteins," scientists in the United States noted.
In a study conducted by E.P. Plant and colleagues at the University of Maryland, "inspection of the overlap regions between ORF1a and ORF1b of the SARS-CoV genome revealed that, similar to all coronaviruses, a programmed -1...
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