Disease Associations
Silicotic nodule formation analyzed, plasma protein roles defined
Published in Respiratory Therapeutics Week, October 3rd, 2005
"The contribution of plasma protein(s) to the stabilization of fibroids formed in rat lungs exposed to acute silica dust inhalation was examined," wrote Y.M. Kim and colleagues, Catholic University of Korea.
"Antibodies against component proteins of the nodules remaining insoluble in 2% SDS, 10 M urea and 40 mM sulfhydryl reagents under prolonged boiling conditions were raised in rabbits and used to capture plasma proteins, which were identified by 2D-gel electrophoresis and MALDI-TOF analysis," the investigators...
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