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Asthma

Research on asthma discussed by scientists at Cleveland Clinic, Department of Molecular Cardiology

Published in Respiratory Therapeutics Week, September 24th, 2007

A new study, "Plasminogen is an important regulator in the pathogenesis of a murine model of asthma," is now available. According to recent research from the United States, "Asthma is a syndrome whose common pathogenic expression is inflammation of the airways. Plasminogen plays an important role in cell migration and is also implicated in tissue remodeling, but its role in asthma has not been defined. To test whether plasminogen is a critical component in the development of asthma."

"We used a mouse model of ovalbumin-induced pulmonary inflammation in Plg(+/+), Plg(±), and Plg(-/-) mice. The host responses measured included lung morphometry, and inflammatory...

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