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Adipose Tissue



Changes in fat mass influence SREBP-1c and UCP-2 gene expression



July 12th, 2005

Changes in fat mass influence SREBP-1c and UCP-2 gene expression in formerly obese subjects.

In a recent article published in the journal Obesity Research, scientists in Italy and France conducted a study "to investigate the effect of fat mass (FM) reduction on adipose tissue gene expression in terms of lipid synthesis [sterol regulatory binding protein 1c (SREBP-1c)] and lipid oxidation [uncoupling protein 2 (UCP-2)] 2 years after lipid malabsorption and to assess the influence of lipid malabsorption on fat-free mass (FFM) maintenance evaluating the expression of genes related to glycolysis [hexokinase (HKII)] and glucose storage [glycogen synthase...


Source: Science Letter (2005-07-12)

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