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Atherosclerosis



Recent findings illuminate research in atherosclerosis



July 12th, 2005

Investigators in Japan and the United States have published new atherosclerosis data.

Study 1: Insulin resistance increases circulating malondialdehyde-modified LDL and impairs endothelial function in healthy young men.

"Endothelial dysfunction is regarded as an early feature of atherosclerosis. Both LDL oxidation and insulin resistance play important roles in the pathogenesis of atherosclerosis. Recent studies have demonstrated a significant association between oxidized LDL and insulin resistance. We investigated relationships between insulin resistance, circulating malondialdehyde-modified (MDA)-LDL, and endothelial function in 36 healthy young...


Source: Science Letter (2005-07-12)

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