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Antithrombotics



Seaweed-derived agent promotes endothelial release of antithrombotic



July 12th, 2005

A novel seaweed-derived compound induces the release of a natural antithrombotic agent from endothelial cells.

"The brown seaweed Spatoglossum schroederi (Dictyotaceae) contains three main fucans (fucans A, B and C) with different mobility in electrophoresis," scientists in Brazil explained.

In a study conducted by H.A.D. Rocha and coauthors at the Federal University of Rio Grande do Norte, the "fucan with highest mobility (fucan C) was precipitated with 2.0 volumes of acetone, purified using a combination of ion exchange chromatography and electrophoresis."

Fucan C "showed an MW of 24 kDa determined by HPLC and Sephadex...


Source: Science Letter (2005-07-12)

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