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Alzheimer Disease



Alzheimer disease modeled, environmental role in cognitive deficits clarified



July 12th, 2005

According to recent research from the United States, environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer disease.

"Epidemiological studies suggest that individuals with greater education or more cognitively demanding occupations have diminished risk of developing dementia. We wanted to test whether this effect could be recapitulated in rodents using environmental enrichment, a paradigm well documented to attenuate behavioral deficits induced by various pathological insults.

"Here," wrote J.L. Jankowsky and colleagues, California Institute of Technology (CALTECH), "we demonstrate that learning and memory deficits...


Source: Science Letter (2005-07-12)

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