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Alzheimer Disease



Enzyme family plays role in Alzheimer disease



July 12th, 2005

The route to a treatment for Alzheimer's disease may have become more straightforward with the discovery that a key enzyme known to have a major role in this disease is in fact part of a family of enzymes. Only some family members play a role in the progression of this brain-wasting illness, new research at the University of Toronto has found.

"It was previously thought that an enzyme called gamma-secretase contributed to the development of protein deposits in the Alzheimer's brain. This study shows that this enzyme is more accurately described as a family of enzymes, each with its own specialization," explains Professor David Westaway of U of T's Centre for Research in...


Source: Science Letter (2005-07-12)

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