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Alzheimer Disease
Humoral responses examined in monkeys vaccinated with A-beta vaccine
July 12th, 2005
Vaccination with the Alzheimer disease-associated beta-amyloid 1-15 peptide vaccine elicited specific humoral immune responses in rhesus monkeys. According to recent research from China, "Alzheimer disease (AD) is a neurodegenerative disorder characterized by overproduction of beta-amylold (A-beta), with the subsequent pathologic deposition of A-beta which is important for memory and cognition. "Recent studies showed murine models of AD and AD patients inoculated with A-beta peptide vaccine had a halted or delayed pathological progression of AD. Unfortunately, the clinical phase IIa trial of A-beta(1-42) peptide vaccine (AN1792) was halted...
Source: Science Letter (2005-07-12)
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