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Alzheimer Disease
Researchers detail new studies and findings in the area of Alzheimer disease
July 12th, 2005
Alzheimer disease data are the focus of recent research from Switzerland, Japan and Sweden. Study 1: Beta-site specific intrabodies prevents generation of Alzheimer's A beta peptide. According to a recent report published in the Journal of Cell Biology, "Endoproteolysis of the beta-amyloid precursor protein (APP) by beta- and gamma-secretases generates the toxic amyloid beta-peptide (A beta), which accumulates in the brain of Alzheimer's disease (AD) patients. "Here, we established a novel approach to regulate production of A beta based on intracellular expression of single chain antibodies (intrabodies) raised to an...
Source: Science Letter (2005-07-12)
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