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Alzheimer Disease



Transfer protein variants were not associated with Alzheimer disease



July 12th, 2005

A recent report describes lack of genetic association of cholesteryl ester transfer protein polymorphisms with late onset Alzheimer disease.

According to recent research published in the journal Neuroscience Letters, "Dysregulation of cholesterol homeostasis may be associated with the pathogenesis of coronary artery disease (CAD) and Alzheimer disease (AD)."

H.Y. Zhu and colleagues of the University Kentucky continued, "Recently, several single nucleoticle polymorphisms (SNPs) in cholesteryl ester transfer protein (CETP) were associated with altered plasma CETP concentrations, cholesterol concentrations and CAD. Hence, these CETP SNPs...


Source: Science Letter (2005-07-12)

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