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Anal Cancer
Patterns of local disease failure and outcome after salvage surgery discussed
July 12th, 2005
Scientists characterized the patterns of local disease failure and outcome after salvage surgery. "Salvage surgery for anal cancer is usually reserved for local disease failure, but issues relating to the prediction of local failure and surgical outcome are ill defined. Between 1988 and 2000, 254 patients with non-metastatic anal epidermoid carcinoma were treated at a regional cancer center with radiotherapy (n=127) or chemoradiotherapy (n=127)," researchers in England reported. "There were 99 local disease failures (39.0 percent), all but 5 occurring within 3 years of initial treatment. Increasing age (p<.001, Cox model), total radiation dose...
Source: Science Letter (2005-07-12)
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