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Hematology
Erdheim-Chester disease was successfully treated with interferon-alpha
December 20th, 2005
Erdheim-Chester disease, a non-Langerhans-cell histiocytosis, was successfully treated with interferon-alpha. According to a study from the United States, "Erdheim-Chester disease is a rare non-Langerhans histiocytosis with multisystem involvement. To date, there is no standard treatment for this disorder, and more than half of the patients succumb within 3 years." F. Braiteh and colleagues at the University Texas in Houston wrote, "Because interferon-alpha promotes the terminal differentiation of histiocytes and dendritic cells, we hypothesized that this molecule would be a useful therapy for Erdheim-Chester disease." The...
Source: Science Letter (2005-12-20)
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