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Allergy & Immunology



Lymphocytes and monocyte CD4 differ in structure and protein association



April 21st, 2006

Recent research from Australia has reported on marked differences in the structures and protein associations of lymphocyte and monocyte CD4.

"The structures, molecular interactions and functions of CD4 in a subset of T lymphocytes have been well characterized. The CD4 receptors of other cell types have, however, been poorly documented.

"We have previously shown that lymphocytes and monocytes/macrophages differ in their expression of CD4 monomers and dimers. In the present study, we have shown further significant differences," wrote G.W. Lynch and colleagues, Australian Red Cross Blood Service.

They explained, "Variability in the...


Source: Science Letter (2006-04-21)

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