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Ampullary Cancer



Ampullary cancer displays prominent angiogenic elements



April 21st, 2006

Ampullary cancer displays prominent angiogenic elements.

Researchers in the People's Republic of China conducted a study "to investigate whether the expression of vascular endothelial growth factor (VEGF) and microvessel density (MVD) are of prognostic significance in ampullary carcinoma. Twenty-two resected tumor specimens from patients with ampullary carcinoma were immunohistochemically stained for VEGF and CD34 (surrogate for vessels) by streptavidin-peroxidase method."

L. Chen and colleagues of Zhejiang University wrote, "Expression of VEGF in tumor tissue was found in 50% of patients. The mean MVD for the entire group was 26.4±12.8. A...


Source: Science Letter (2006-04-21)

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