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Angiology



Homocysteine-induced endothelial dysfunction is augmented by iron sucrose in normal subjects



April 21st, 2006

Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects.

According to recent research published in the journal Kidney International, "Intravenous iron is commonly used in conjunction with erythropoietic agents to treat anemia in patients with chronic kidney disease. Iron has been proposed to promote oxidative stress and endothelial dysfunction in vascular tissues."

H. Zheng and colleagues at Yale University School of Medicine explained, "We studied the acute effects of intravenous iron sucrose on homocysteine-induced endothelial dysfunction in the brachial artery of normal human subjects. In all, 40 healthy...


Source: Science Letter (2006-04-21)

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