Science Letter
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Science Letter
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Angiology
Myosin phosphatase isoform switching may determine responses to NO/cGMP signaling
April 21st, 2006
Researchers propose that myosin phosphatase isoform switching during neonatal vascular smooth muscle phenotypic specification may determine changing vascular responses to NO/cGMP signaling in the transition from the fetal to the adult circulation. According to scientists publishing in the Journal of Molecular and Cellular Cardiology, "We are using the myosin phosphatase targeting subunit (MYPT1) as a model gene to study smooth muscle phenotypic diversity. Myosin phosphatase (MP) is the primary effector of smooth muscle relaxation, and MYPT1 is a key target of signals that regulate smooth muscle tone." M.C. Payne and colleagues at Case Western...
Source: Science Letter (2006-04-21)
|
