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Angiology
Protein tyrosine phosphatase inhibition improves vascular endothelial dysfunction
April 21st, 2006
Inhibition of protein tyrosin phosphatase improves vascular endothelial dysfunction in diabetes mellitus and hyperhomocysteinemia patients. According to a report from India, "The study has been designed to investigate the effect of Bis-(maltolato) oxovanadium (BMOV), an inhibitor of protein tyrosin phosphatase (PTPase), in diabetes mellitus and hyperhomocysteinemia-induced vascular endothelial dysfunction." D.I. Shah and M. Singh working with Punjabi University described their procedure, "Streptozotocin (55 mg kg-1, i.v.) and methionine (1.7% w/w, p.o., 4 weeks) were administered to rats to produce diabetes mellitus (serum glucose >140...
Source: Science Letter (2006-04-21)
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