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Anorexia Nervosa



d-fenfluramine reduces water intake, but not food intake, in activity-based anorexia



April 21st, 2006

The appetite suppressant d-fenfluramine reduces water intake, but not food intake, in activity-based anorexia.

According to recent research from Netherlands, "Biochemical, genetic and imaging studies support the involvement of the serotonin (5-HT) system in anorexia nervosa. Activity-based anorexia (ABA) is considered an animal model of anorexia nervosa, and combines scheduled feeding with voluntary running wheel activity (RWA)."

J.J.G. Hillebrand and colleagues working with the University of Utrecht examined, "the effect of d-fenfluramine (d-FEN) treatment on development and propagation of ABA. d-FEN is an appetite suppressant and acts on 5-HT2C...


Source: Science Letter (2006-04-21)

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